| Time | Matchup | Prediction | Actual | Result |
|---|
| 9/16/2022 7:30 PM |  Florida State @ Louisville 
by 2.5 | Florida State wins 44.0-15.6 won 95.92% of sims, average margin of 28.4
| Florida State wins 35-31
|   |
| 9/24/2022 12 PM |  USF @ Louisville
by 13 | Louisville wins 37.1-18.6 won 84.73% of sims, average margin of 18.5
| Louisville wins 41-3
| |
| 10/1/2022 12 PM | Louisville @ Boston College 
by 13 | Louisville wins 32.2-12.8 won 88.70% of sims, average margin of 19.4
| Boston College wins 34-33
|  |
| 10/8/2022 12 PM | Louisville @ Virginia 
by 3.5 | Virginia wins 23.0-18.7 won 58.99% of sims, average margin of 4.3
| Louisville wins 34-17
| |
| 10/22/2022 8 PM |  Pittsburgh @ Louisville
by 2.5 | Louisville wins 31.4-22.3 won 68.37% of sims, average margin of 9.1
| Louisville wins 24-10
|  |
| 10/29/2022 3:30 PM |  Wake Forest @ Louisville
by 4 | Louisville wins 31.2-22.8 won 67.21% of sims, average margin of 8.4
| Louisville wins 48-21
| |
| 11/5/2022 7:30 PM |  James Madison @ Louisville
by 7 | Louisville wins 48.3-8.7 won 99.51% of sims, average margin of 39.6
| Louisville wins 34-10
| |
| 11/12/2022 3:30 PM | Louisville @ Clemson 
by 7 | Clemson wins 27.7-23.9 won 59.20% of sims, average margin of 3.8
| Clemson wins 31-16
| |
| 11/19/2022 3:30 PM |  NC State @ Louisville
by 4 | Louisville wins 27.5-19.2 won 71.13% of sims, average margin of 8.3
| Louisville wins 25-10
| |
| 11/26/2022 3 PM | Louisville @ Kentucky 
by 3.5 | Louisville wins 24.6-20.9 won 59.08% of sims, average margin of 3.7
| Kentucky wins 26-13
| |
| 12/17/2022 11 AM |  Cincinnati @ Louisville
by 1.5 | Louisville wins 24.8-21.5 won 59.27% of sims, average margin of 3.3
| Louisville wins 24-7
| |
