| Date/Time | Matchup/Odds | Prediction | Actual | Result |
|---|
| 11/9/2021 8 PM |  Kennesaw State @ Iowa State 
by 15.5 |
| Iowa State wins 84-73
| |
| 11/12/2021 8 PM |  Oregon State @ Iowa State
by 1.5 |
| Iowa State wins 60-50
| |
| 11/16/2021 8 PM |  Alabama State @ Iowa State
by 22.5 | Iowa State wins 79.5-62.2 won 90.94% of sims, average margin of 17.3
| Iowa State wins 68-60
|   |
| 11/21/2021 6 PM |  Grambling State @ Iowa State
by 17.5 | Iowa State wins 76.6-54.2 won 97.19% of sims, average margin of 22.4
| Iowa State wins 82-47
| |
| 11/24/2021 7 PM |  Xavier @ Iowa State
by 9 | Xavier wins 66.4-62.3 won 61.84% of sims, average margin of 4.0
| Iowa State wins 82-70
|  |
| 11/26/2021 9 PM | Iowa State @ Memphis 
by 11.5 | Iowa State wins 71.3-71.1 won 51.09% of sims, average margin of 0.2
| Iowa State wins 78-59
| |
| 12/1/2021 8 PM |  Arkansas Pine Bluff @ Iowa State (17)
by 26.5 | Iowa State wins 81.8-55.6 won 96.88% of sims, average margin of 26.2
| Iowa State wins 83-64
| |
| 12/4/2021 9 PM | Iowa State @ Creighton 
by 4.5 | Iowa State wins 73.3-69.4 won 59.35% of sims, average margin of 3.9
| Iowa State wins 64-58
|  |
| 12/9/2021 9 PM |  Iowa (15) @ Iowa State
by 5 | Iowa wins 78.2-70.9 won 70.00% of sims, average margin of 7.3
| Iowa State wins 73-53
| |
| 12/12/2021 1 PM |  Jackson State @ Iowa State (21)
by 18.5 | Iowa State wins 69.6-58.7 won 77.27% of sims, average margin of 10.9
| Iowa State wins 47-37
| |
| 12/19/2021 1 PM |  Southeastern Louisiana @ Iowa State (21)
by 20.5 | Iowa State wins 78.7-62.7 won 86.36% of sims, average margin of 16.0
| Iowa State wins 77-54
| |
| 12/21/2021 7 PM |  Chicago State @ Iowa State (23)
by 27.5 | Iowa State wins 69.3-51.0 won 92.50% of sims, average margin of 18.3
| Iowa State wins 79-48
| |
| 1/1/2022 2 PM |  Baylor (6) @ Iowa State (24)
by 7.5 | Baylor wins 72.8-70.8 won 53.64% of sims, average margin of 2.1
| Baylor wins 77-72
| |
| 1/5/2022 9 PM |  Texas Tech @ Iowa State (25)
by 2.5 | Iowa State wins 70.6-65.6 won 63.91% of sims, average margin of 5.1
| Iowa State wins 51-47
| |
| 1/8/2022 6 PM | Iowa State (23) @ Oklahoma 
by 5.5 | Oklahoma wins 69.7-66.1 won 60.00% of sims, average margin of 3.6
| Oklahoma wins 79-66
| |
| 1/11/2022 8 PM | Iowa State @ Kansas (12) 
by 11 | Kansas wins 77.4-60.6 won 89.47% of sims, average margin of 16.9
| Kansas wins 62-61
| |
| 1/15/2022 2 PM |  Texas (12) @ Iowa State (25)
by 2 | Iowa State wins 70.3-62.7 won 72.27% of sims, average margin of 7.6
| Iowa State wins 79-70
| |
| 1/18/2022 9 PM | Iowa State (20) @ Texas Tech (17)
by 7.5 | Texas Tech wins 70.6-64.2 won 66.52% of sims, average margin of 6.4
| Texas Tech wins 72-60
| |
| 1/22/2022 4 PM |  TCU @ Iowa State
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| 1/26/2022 | Iowa State @ Oklahoma State 
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| 1/29/2022 |  Missouri @ Iowa State
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| 2/1/2022 | Kansas @ Iowa State
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| 2/5/2022 | Iowa State @ Texas
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| 2/8/2022 | Iowa State @ West Virginia 
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| 2/12/2022 |  Kansas State @ Iowa State
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| 2/15/2022 | Iowa State @ TCU
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| 2/19/2022 | Oklahoma @ Iowa State
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| 2/23/2022 | West Virginia @ Iowa State
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| 2/26/2022 | Iowa State @ Kansas State
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| 3/2/2022 | Oklahoma State @ Iowa State
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| 3/5/2022 | Iowa State @ Baylor
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